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PVP K30 (Pharmaceutical-grade) Applied for Pharmaceutical Excipients
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PVP K30 (Pharmaceutical-grade) Applied for Pharmaceutical Excipients

Name: Polyvinylpyrrolidone (PVP K30)
Abbreviation: Povidone K30
CAS Number: 9003-39-8
Molecular formula: (C6H9NO)n
Appearance (Colour):  White or off-white powder
 
Polyvinylpyrrolidone K30 is used as a powder and solution in the production of pharmaceutical tablets because of its adhesion properties. This substance is completely compatible and does not interact to other tablet components. PVP K30 can form a kind of clear solution quickly, so it is suitable to produce high-solubility tablets and can be used as a solubility enhancer in polar solvents for topical and oral applications. In addition, PVP K30 also plays an important role in emulsion stability and anti-sedimentation and it applys for a binder in a variety of oral tablets, film forming in coated tablets and stabilization of suspensions.
  • PVP K30 (Pharmaceutical-grade)

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Polyvinylpyrrolidone PVP K30-pharmaceutical grade

111In the feld of phamaceutica, PVP-K30 is a new and excellent pharmaceutical excipient. It is mainly used as binder for tablet and pellet, dissolving assistant for injection and the assistant for capsule as well as dispersant for liquid, medicine and stain. Stabilizer for enzyme andheat sensitive drug, coprecipitant for poorly soluble drugs, lubricator and antitoxic assistant for eye drug. Polyvinylpyrrolidone, due to its chemical structure (the presence of a lactam ring), can form a complex with many molecules containing functional groups such as hydroxyl, carboxylic and amine. 

As for the sustained-release agents themselves, the current research focus is the preparation of relatively complex drugs, energy efficient release, rake therapy, and have obvious drug control of the focus, such as layered particles, microspheres, microcapsules and nanoparticles. It can also be used as a drug carrier to ensure that the drug is released in the human body for a long time. In addition, PVP K30 can be used as binder, excipient, coating agent, solvent enhancer, sustained release agent, capsule shell, film forming agent and so on in the field of medicine and healthcare. In some developed countries, such as the United States, Germany, Japan, etc., the application of PVP in the field of medicine and health accounts for about 40% ~ 55% of the total consumption of PVP.


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